Evidence for the Management of Bronchopulmonary Dysplasia in Very Preterm Infants
نویسندگان
چکیده
Background: Very preterm birth often results in the development of bronchopulmonary dysplasia (BPD) with an inverse correlation gestational age and birthweight. This very population is especially exposed to interventions, which affect BPD. Objective: The goal our review summarize evidence on these daily procedures provide evidence-based recommendations for management Methods: We conducted a systematic literature research using MEDLINE/PubMed antenatal corticosteroids, surfactant-replacement therapy, caffeine, ventilation strategies, postnatal inhaled nitric oxide, bronchodilators, macrolides, patent ductus arteriosus, fluid management, vitamin A, treatment pulmonary hypertension stem cell therapy. Results: Evidence provided by meta-analyses, reviews, randomized controlled trials (RCTs) large observational studies are summarized as narrative review. Discussion: There strong use combination noninvasive caffeine lung-protective strategies. A more differentiated approach has be applied corticosteroid treatment, arteriosus (PDA), fluid-intake supplementation, well BPD-associated hypertension. no routine bronchodilators prophylactic oxide. Stem therapy promising, but should used RCTs only.
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ژورنال
عنوان ژورنال: Children (Basel)
سال: 2021
ISSN: ['2227-9067']
DOI: https://doi.org/10.3390/children8040298